The MathWorks, Inc. [http://www.mathworks.com/] styles MATLAB [http://www.mathworks.com/products/] as "the language of technical computing". MathWorks is an interesting company; it continued to hire programmers all through 2002 and at least the beginning of 2003, despite the general depression in [IT]. The quickest, lightest way to get [Tcl] and MATLAB talking is through [DDE]. MATLAB also exposes a [COM] interface that permits essentially fully general control, although it's documented with as much mystery as seems to be canonical with COM. Paul McGuire has documented his experience in COM control [http://www.geocities.com/ptmcg/python/using_matlab_from_python.html] with [Python]; most of this knowledge translates easily to Tcl. [TMath] and [TCL-MAT] both bind Tcl and MATLAB. [Octave] is an open-source replacement for MATLAB. Perhaps [NAP] is also of interest. [[Link to article on Open Source vs. proprietary for scientists, available through [http://phaseit.net/claird/comp.programming/open_source_science.html].]]