Enterprise Resource Planning
Just a few years ago, toward the end of the '90s, ERP epitomized Big, Serious Programming. It was entirely comparable to such more recent management fads as CRM, EAI, eBusiness, ... If anything, it has a less ambiguous ROI than these others.
Remarkably, given all the grief heard about how the only applications in Tcl and Tcl/Tk are "toys", there's at least on ERP package [L1 ] written in Tcl/Tk.