http://purl.org/tcl/home/man/tcl8.5/TclCmd/fconfigure.htm
An important use is
fconfigure $binaryDataFile -translation binary
to make sure the file is read as binary data.
LV 2008 Feb 28
Some of the wiki pages talk about the construct
fconfigure $serial_port -mode "$baudRate,$plex,$bits,$polarity"
or some such thing. The -mode flag, used for specifying baud rate, etc. has moved to open now. I don't know how one would change those values on an open descriptor...